A new biography, Dr. M

New York, NY (PRWEB) September 04, 2014

Based on 15 years of study and illustrated with dozens of historical (and exclusive) photographs, DR. MÜTTER’S MARVELS: A Accurate Tale of Intrigue and Innovation at the Dawn of Contemporary Medicine (Gotham September four, 2014) delves deep into the life of a man who was really ahead of his time.

Written by poet and author Cristin O’Keefe Aptowicz, the book reveals Mütter’s early years as an orphan and time spent studying cutting-edge surgery in Paris, to his struggles to establish himself in Philadelphia amidst the outrageous rivalries amongst his fellow doctors—many of whom publicly mocked Mütter’s philosophies and innovations, including his devotion to pre-and post-operative care, employing anesthesia, and even the sterilization of his tools.

The deluxe eBook edition of DR. MÜTTER’S MARVELS involves more than a single hour of audio in which author Cristin O’Keefe Aptowicz shares information, stories and insights about Dr. Mütter and his contemporaries that she found in her study but didn’t make it into the printed book.

By way of Mütter’s humanist eyes, we are given a front row seat to the evolution of American medicine: from bleedings and leechings to the standardization of healthcare schools from the discovery of anesthesia to his community’s frustrating resistance to washing hands and sterilizing tools from the unimaginable medical circumstances provoked from the rise of industrialism, to the challenges and innovations birthed as the nation marched toward the Civil War.

Even though he only lived for 47 years, Mütter’s influence within medicine is nonetheless felt, and his legacy lives on with his enormously well-liked namesake museum. And now, with DR. MÜTTER’S MARVELS, his strange, inspiring and untold story can finally be shared.

Highlight Reel


**Read the Wall Street Journal’s front web page review of Dr. Mütter’s Marvels.


**USA Today mentions Dr. Mütter in “The Week in Books.”


**A.V Club calls Dr. Mütter’s Marvels “narrative non-fiction at its ideal.”


**Study the Asbury Park Press interview with Cristin O’Keefe Aptowicz.


**BookPage testimonials Dr. Mütter’s Marvels, calling it “an insightful portrait of a pioneering surgeon and a reminder of how far medicine has come.”


**Read Library Journal’s starred evaluation in the September 1st concern.


**Publishers Weekly announced Dr. Mütter’s Marvels in Galley Talk.


**Read the Publishers Weekly starred assessment of Dr. Mütter’s Marvels, calling Aptowicz’s writing “as complete of life as her topic.”


**Read Kirkus Testimonials starred assessment of Dr. Mütter’s Marvels, “the author offers an absorbing account of the charismatic surgeon’s life and career as nicely as a vivid appear at the health-related practices and prejudices of his time.”


**Mashable writes “If You Think ‘The Knick’ Individuals Have it Negative … Go Back 50 Years.”


**Read the Metro Philadelphia interview with Cristin O’Keefe Aptowicz

ABOUT THE AUTHOR:


Cristin O’Keefe Aptowicz is the author of six books of poetry (most lately, The Year of No Blunders) as properly as the nonfiction book, Words In Your Face: A Guided Tour By means of Twenty Years of the New York City Poetry Slam, which Billy Collins wrote “leaves no doubt that the slam poetry scene has achieved legitimacy and taken its rightful spot on the map of contemporary literature.”

On the National Endowment for the Arts (NEA) podcast Art Works, host Josephine Reed introduced Cristin as getting “something of a legend in NYC’s slam poetry scene. She is lively, thoughtful, and approachable looking to engage the audience with her function and deeply committed to the community that art … can generate.”

In July 2010, she was named the 2010-2011 ArtsEdge Writer-in-Residence at the University of Pennsylvania, where she spent the year researching and writing a book on Thomas Dent Mütter, founder of the Philadelphia’s (in)popular Mütter Museum. She would also be awarded a 2011 National Endowment for the Arts Fellowship in Poetry and an Amy Clampitt Home residency, both of which helped to help the finishing of this book.

CATCH CRISTIN ON TOUR IN 2014

9/four/14, Philadelphia, PA: Book Release


9/five/14, Philadelphia, PA: The Rotunda


9/eight/14, Philadelphia, PA: University of Pennsylvania


9/9/14, New York, NY: Urbana Poetry Slam


9/ten/14 (noon), West Windsor, NJ: Mercer College


9/10/14 (7pm), Brooklyn, NY: Morbid Anatomy Museum


9/13/14, New York, NY: Magnet Theater


9/15/14 (1-3pm), Reddit.com: Reddit AMA


9/16/14, Philadelphia, PA: Free of charge Library of Philadelphia


9/19/14, Austin, TX: Bookpeople


9/24/14, Columbus, OH: Writer’s Block Poetry Slam


9/25/14, Columbus, OH: Writer’s Block Workshop


9/26/14, Columbus, OH: Book Loft


9/28/14, Ann Arbor, MI: Nicola’s Bookstore


10/four/14, Chicago, IL: Quimby’s Bookstore


10/five/14, Chicago, IL: Green Mill Poetry Slam


ten/11/14, Minneapolis, MN: Encyclopedia Show


10/13/14, Minneapolis, MN: Magers &amp Quinn Bookseller


ten/14/14, Minneapolis, MN: Storytelling Show


10/15/14, Minneapolis, MN: The Loft Literary Center


ten/16/14, Mankato, MN: University of MN, Mankato


ten/17/14, Omaha, NE: Louder than a Bomb Workshop


10/18/14, Omaha, NE: The Bookworm


ten/18/14, Omaha, NE: Louder than a Bomb Fundraiser


10/20/14, Iowa City, IA: Prairie Lights Bookstore


ten/25/14, Austin, TX: Texas Book Festival


10/26/14, Austin, TX: Texas Book Festival


11/three/14, Portland, OR: Powell’s City of Books


11/four/14, Seattle, WA: Seattle Poetry Slam


11/five/14, Seattle, WA: Rain City Poetry Slam


11/eight/14, Seattle WA: Elliott Bay Book Company


11/12/14, Vancouver, CANADA: Vancouver Poetry Slam


11/13/14, Vancouver, CANADA: Book Warehouse




Gotham Books | September 2014 | Hardcover | eBook| Deluxe eBook


978-1592408702 | 384 pp


Also obtainable as Penguin Random House Digital Audio

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NJIT Researcher Receives New NSF Funding to Study Basic Rhythms of Life

(PRWEB) August 27, 2014

Casey Diekman, assistant professor of mathematical sciences at New Jersey Institute of Technology (NJIT), is helping to acquire greater insight into the biological clock that sets the pace for day-to-day life.

Evolution has harmonized the behavior of humans and all other mammals with fundamental rhythms of life that include the cycle of light and dark knowledgeable each day and with seasonal modify. The brain’s circadian clock controls hormone production connected to all-natural patterns of sleep/wake behavior which, when disrupted by experiences such as jet lag or night-shift operate, can have adverse overall health effects. It is a crucial physiological procedure intrinsic to our mood and alertness, but one that has yet to be completely understood.

Gaining higher insight into the biological clock that sets the pace for every day life is the focus of a transatlantic analysis work involving Casey Diekman, assistant professor in NJIT’s Division of Mathematical Sciences. Diekman’s function, which is getting funded by a 3-year grant of a lot more than $ 233,000 from the National Science Foundation (NSF), could yield new knowledge for the U.S. national BRAIN Initiative — an acronym for Brain Analysis by means of Advancing Revolutionary Neurotechnologies.

Model Contributions

Diekman joined the NJIT faculty in 2013, after post-doctoral perform at the NSF-funded Mathematical Biosciences Institute at Ohio State University. His principal goal as the NSF grant’s principal investigator is to create mathematical models that will market understanding of the function that our internal clock’s electrical activity plays in circadian timekeeping, in certain the way the clock responds to the all-natural light/dark cycle.

Diekman is collaborating with Professor Hugh Piggins and Investigation Associate Mino Belle at the University of Manchester in England. Piggins’ laboratory is supplying experimental biological information about electrical activity in the brain at the cellular level, especially with respect to the influence of dynamic changes in gene expression on neurons in the suprachiasmatic nucleus, or SCN. Gene expression is the method by which DNA is translated into proteins, and proteins are the engines of most physiological functions, which includes circadian behavior.

A group of about 20,000 neurons in the hypothalamus, the SCN receives details about the light/dark cycle from the external globe via the retina that can have an effect on the circadian method. “The job of this element of brain is to know what time of day it is,” Diekman says succinctly. It is a job that the SCN also may do without having direct exposure to external light/dark conditions.

Two Vastly Diverse Time Scales

At the neuronal level, the interplay of several ionic currents within SCN neurons produces electrical oscillations on the time scale of milliseconds. Eventually, these electrical signals add up to our day-to-day behavior patterns. Experimentally, the challenge has been to gather information about these currents below precisely controlled light/dark situations in order to study how SCN activity may possibly differ more than a specific period, such as 24 hours. Even though collecting this data is a really labor-intensive procedure, it offers the raw material for Diekman’s mathematical modeling.

A key objective of the resulting model is to integrate the experimental data into a extensive physiological portrait to simulate neuronal activity and clarify the discrete roles of various ionic currents, Diekman explains. And a key mathematical objective is to take details about biological events that happen on a millisecond time scale and establish how they collectively influence 24-hour behavioral patterns. The model can then be employed to make predictions about the circadian time-keeping process that can be verified in the laboratory, and to recommend new experiments that will add to our information in this area.

“We want to recognize the interaction among two various biological ‘oscillators’ operating on two vastly various time scales,” Diekman says.

Preliminary outcomes obtained by Diekman and his research colleagues suggest that the circadian rhythms they are studying comprise a actually intrinsic approach rooted in “hard-wired” neuronal electrical programming. More specifically, as suggested by Diekman’s modeling, the neurons in the SCN will start to enter a state where they are significantly less active in the afternoon. In this state, the neurons’ electrical activity has an specially pronounced effect on gene expression, influencing hormone production and other physiological indicators without having external light/dark exposure. It is a rhythm deeply encoded in our DNA.

As a element of the BRAIN Initiative, Diekman’s work has broader implications as well. He anticipates that deeper understanding of the flow of data involved at the cellular level will aid in the improvement of mathematical models of brain processes such as long-term memory formation. The project also could impact places of mathematical biology beyond circadian rhythms by advancing improvement of laptop-simulation techniques capable of handling broadly disparate time scales.

About NJIT


One particular of the nation’s major public technological universities, New Jersey Institute of Technologies (NJIT) is a best-tier analysis university that prepares students to turn out to be leaders in the technologies-dependent economy of the 21st century. NJIT’s multidisciplinary curriculum and computing-intensive approach to education provide technological proficiency, organization acumen and leadership expertise. With an enrollment of far more than 10,000 graduate and undergraduate students, NJIT delivers small-campus intimacy with the sources of a key public investigation university. NJIT is a worldwide leader in such fields as solar study, nanotechnology, resilient design, tissue engineering, and cyber-safety, in addition to other people. NJIT ranks 5th among U.S. polytechnic universities in study expenditures, topping $ 110 million, and is among the prime 1 % of public colleges and universities in return on educational investment, according to PayScale.com.njit

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Lasers can improve the life of coin dies, save on production costs and make them more desirable to numismatists

London, UK (PRWEB UK) 13 May 2014

Mints have been around for countless decades, but recently the technology used in the production process has advanced dramatically. With the increased introduction of lasers in the coin die process, mints are able to lower their production costs and numismatists provided with coins that will carry intricate designs that are as close to perfection as possible.

According to an article published by Numismatic News on April 8, 2014, the company that is spearheading this new technology is FOBA Laser Marking & China Engraving Solutions. FOBA’s new laser die process will replace the old and now dated CNC milling processes that was not only labour intensive, but also prone to human error and blemishes that included die cracks and raised lines. Something that led to further time and labour being required to prepare the die for use.

The ability to engrave the desired coinage images directly onto the die after that die has gone through the hardening process will produce cleaner and more intricate designs on the surface of coins. For numismatists this will mean being able to add uniquely designed coins to their collections, keep them for extended periods of time whilst their value increases, and then sell them on looking almost as good as new.

In addition to the labour and cost saving advantages in the die production process for mints, FOBA’s GP9000 laser engraving machine also offers additional advantages that might not otherwise be able to be utilised for additional coinage security. Security features such as micro inscriptions and micrometer-size symbols can be added to a working die in a consistent and extremely accurate way, that way saving time previously taken by a die engraver to manually craft the image.

Elliot Basker, Online Business Manager, Hallmark Coins, said, “Although the coin production process has been around for decades, these giant strides made in the die cast process can and will lead to some rather intricate and breath taking coin designs in the future. “These designs will not only stand the test of time when it comes to preserving the aesthetic and investment appeal of the coins for future numismatists, but also allow mints to dramatically reduce their production costs.”

The laser technology offers significant advantages when die China manufacturing requirements exceed the limits of what can be done using traditional mechanical processes. Saving mints time and money and ensuring the production of superior quality coins in the future that are visually appealing for numismatists.

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